Acetyl-L-Carnitine is an immediate byproduct of metabolism that combines with CoA supplied by Vitamin B5 to produce Acetyl-CoA and Carnitine. At this stage in the process, this newly created Acetyl molecule is then able to join the Acetyl group of the acetylcholine molecule. Research has shown that Acetyl-L-Carnitine may also reduce mental and physical fatigue*.
Artichoke Leaf Extract
Artichoke extract contains Luteolin, a natural inhibitor of PDE4 [6,7]. PDE4 is an enzyme that breaks down cAMP molecules, messenger systems that relay signals in the brain. Studies have correlated lower levels of the enzyme PDE4 to significant increases in normal mental performance, including increased cognition [8], improved long term memory [9], increased wakefulness [10], and neuroprotection. [11,12,13]
Coleus forskohlii
Forskolin is derived from the plant Coleus forskohlii which has been widely used in traditional Ayurvedic medicine [4]. It has also has been extensively studied due to it’s ability to increase levels of intracellular cAMP molecules [5]. Combined with Luteolin from Artichoke Extract, forskolin is theorized to synergistically increase the duration of cAMP in neurons.
L-Phenylalanine
L-Phenylalanine and L-Tyrosine are amino acid precursors to dopamine - both must be present in order for dopamine to be synthesized. L-Phenylalanine is present in many foods (such as meat and dairy), and is converted into L-Tyrosine in the body. In turn, L-Tyrosine is converted into L-Dopa, the direct precursor to dopamine.*
Vitamin B6
Vitamin B6 helps convert L-Dopa into dopamine and Vitamin C helps convert dopamine into norepinephrine (increasing alertness and attention).* Each of these also have important antioxidant properties that protect cells from damage during the production and metabolism of dopamine.*
How To Use
What To Expect
Citations
How To Use
x15 servings
Each bottle of Neurofuel contains 15 servings. Recommended daily serving is 3 capsules per day.
Warning: If you are pregnant, nursing, or taking medications, consult a healthcare practitioner before use.
1-3 capsules/day
Take 1-3 capsules in the morning immediately upon waking on an empty stomach, or as directed by a healthcare practitioner. Do not take more than 3 capsules per day.
For maximum benefits, we advise taking up to 5-6 days a week.
What To Expect
"Neurofuel has been a game changer! It's been doing wonders for my attention and motivation."
- Jessica J.
"I felt more productive and focused compared to before I started using Neurofuel."
- Derek L.
"I love this product. It gives me a smooth long lasting clarity. Improves my focus, I love taking it before reading and stack it with my coffee."
- Patricia R.
Citations
[1] Scafidi S, Fiskum G, Lindauer SL, et al. Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain. Journal of neurochemistry. 2010;114(3):820-831. doi:10.1111/j.1471-4159.2010.06807.x.
[3] Reneerkens OAH, Rutten K, Steinbusch HWM, Blokland A, Prickaerts J. A promising target for cognition enhancement. Psychopharmacology. 2009;202(1-3):419-443. doi:10.1007/s00213-008-1273-x.
[4] Ammon HP, Müller AB. Forskolin: from an ayurvedic remedy to a modern agent. Planta Med. 1985;51(6):473-7. PMID 17345261
[6] Brown JE, Rice-evans CA. Luteolin-rich artichoke extract. Free Radic Res. 1998;29(3):247-55. PMID 9802556 32
[7] Yu MC, Chen JH, Lai CY, Han CY, Ko WC. Eur J Pharmacol. 2010;627(1-3):269-75. PMID 19853596
[8] Rutten K, Van donkelaar EL, Ferrington L, et al. Neuropsychopharmacology. 2009;34(8):1914-25. PMID 19262466
[9] Reneerkens OAH, Rutten K, Steinbusch HWM, Blokland A, Prickaerts J. A promising target for cognition enhancement. Psychopharmacology. 2009;202(1-3):419-443. doi:10.1007/s00213-008-1273-x.
[10] Barad M, Bourtchouladze R, Winder DG, Golan H, Kandel E. Proc Natl Acad Sci USA. 1998;95(25):15020-5. PMID 9844008
[11] Lelkes Z. Pharmacol Biochem Behav. 1998 Aug;60(4):835-9.
[12] Block F1. Neuroreport. 2001 May 25;12(7):1507-11.
[13] Chen RW. Neurosci Lett. 2007 May 17;418(2):165-9. Epub 2007 Mar 18.
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We suggest taking NEUROFUEL™ first thing in the morning on days that include demanding cognitive tasks. Take it on an empty stomach and 20-30 minutes later, you eat breakfast or - our favorite, have some bulletproof coffee for an extra spark.
NEUROFUEL™ increases focus and potentiates long-term memory but doesn't rely on neurotransmitter manipulation to elicit this benefit. Because NEUROFUEL™ is not a stimulant and it doesn’t directly impact our neurotransmitters, the “feel” is very subtle. What you notice most is that time seems to slow, distractions fade away (increased focus), and you have a strong desire to learn/read/work. The more mentally demanding the task, the more NEUROFUEL™ shines. Many users prefer to “stack” or combine NEUROFUEL™ with one of our Brain Food products. The Brain Food line is designed to give individuals the tools needed to optimize whatever neurotransmitter they may need to moderate on any given day or at any given time.
NEUROFUEL™ is a natural nutritional supplement designed for improving and maintaining brain performance. It's theorized to improve learning and memory in the brain by supporting and optimizing levels of intracellular secondary messengers.
There are no known side effects if used as directed. For that reason, thousands of people have chosen all-natural NEUROFUEL™ as their preferred nootropic stack.
NEUROFUEL™ works best on an empty stomach. You'll feel the fuel fast, within 30 minutes of your first dose. Due to the effects it's recommended to take NEUROFUEL™ during the daytime or early afternoon.
NEUROFUEL™ uses a simple, all-natural formula that works by increasing the number of messenger systems inside of your brain cells. This enables neurons to quickly communicate with each other and retain information. It makes you more engaged and efficient at whatever mental task you might be doing. NEUROFUEL™ enhances your mental capacity without relying on altering neurotransmitter levels. It acts inside of the cell to naturally strengthen connections between neurons, promoting improved learning, memory, and cognitive function.
