NEUROFUEL™ is the original CILTEP® formula for enhanced focus, deep concentration and improved memory.
The premium natural ingredients work as fuel for your neurotransmitters, supporting greater signaling between brain cells.
FEEL THE FUEL within 30 minutes of your first dose.
Smart Caffeine is a highly effective combination of L-theanine and Caffeine. L-theanine is a natural amino acid found in green tea that removes the undesirable side effects of caffeine, creating long-lasting energy and attention without jitters, anxiety, or a crash.
Creates a relaxed yet alert state that is ideal for focusing and thinking clearly.
Supports a relaxed but alert state that is ideal for productive, focused activity - mental or physical.
Research has shown that Acetyl-L-Carnitine may reduce mental and physical fatigue*.
L-theanine is a natural amino acid found in green tea that removes the undesirable side effects of caffeine, creating long-lasting energy and attention without jitters, anxiousness, or a crash. A recent study from The Netherlands confirmed that "The combination of L-Theanine and Caffeine improves the cognitive performance and increases subject alertness." and that the combination "helps to focus attention during a demanding cognitive task." [1]
Acetyl-L-Carnitine is an immediate byproduct of metabolism that combines with CoA supplied by Vitamin B5 to produce Acetyl-CoA and Carnitine. At this stage in the process, this newly created Acetyl molecule is then able to join the Acetyl group of the acetylcholine molecule. Research has shown that Acetyl-L-Carnitine may also reduce mental and physical fatigue*.
Artichoke extract contains Luteolin, a natural inhibitor of PDE4 [6,7]. PDE4 is an enzyme that breaks down cAMP molecules, messenger systems that relay signals in the brain. Studies have correlated lower levels of the enzyme PDE4 to significant increases in normal mental performance, including increased cognition [8], improved long term memory [9], increased wakefulness [10], and neuroprotection. [11,12,13]
Forskolin is derived from the plant Coleus forskohlii which has been widely used in traditional Ayurvedic medicine [4]. It has also has been extensively studied due to it’s ability to increase levels of intracellular cAMP molecules [5]. Combined with Luteolin from Artichoke Extract, forskolin is theorized to synergistically increase the duration of cAMP in neurons.
L-Phenylalanine and L-Tyrosine are amino acid precursors to dopamine - both must be present in order for dopamine to be synthesized. L-Phenylalanine is present in many foods (such as meat and dairy), and is converted into L-Tyrosine in the body. In turn, L-Tyrosine is converted into L-Dopa, the direct precursor to dopamine.*
Neurofuel: 15 servings
Smart Caffeine: 60 servings
Warning: If you are pregnant, nursing, or taking medications, consult a healthcare practitioner before use.
Neurofuel: Take up to 3 capsules/day
Smart Caffeine: Take a serving of 1-2 capsules whenever focused energy is desired. Avoid use in the evening.
"The one two punch that hotwires the brain"
"I love both of these products. I use the Smart Caffeine nearly daily. Such a better way to go than Preworkouts or other stimulants. Well done!"
"Love this stuff I think clearer and no brain fog at all its amazing."
[1] Scafidi S, Fiskum G, Lindauer SL, et al. Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain. Journal of neurochemistry. 2010;114(3):820-831. doi:10.1111/j.1471-4159.2010.06807.x.
[2] Pettegrew, JW. Molecular Pyschiatry. Nov. 2000, Volume 5, Number 6, Pages 616-632.
[3] Reneerkens OAH, Rutten K, Steinbusch HWM, Blokland A, Prickaerts J. A promising target for cognition enhancement. Psychopharmacology. 2009;202(1-3):419-443. doi:10.1007/s00213-008-1273-x.
[4] Ammon HP, Müller AB. Forskolin: from an ayurvedic remedy to a modern agent. Planta Med. 1985;51(6):473-7. PMID 17345261
[5] Jongkees BJ, Hommel B, Colzato LS. People are different: tyrosine’s modulating effect on cognitive control in healthy humans may depend on individual differences related to dopamine function. Frontiers in Psychology. 2014;5:1101. doi:10.3389/fpsyg.2014.01101.
[6] Brown JE, Rice-evans CA. Luteolin-rich artichoke extract. Free Radic Res. 1998;29(3):247-55. PMID 9802556 32
[7] Yu MC, Chen JH, Lai CY, Han CY, Ko WC. Eur J Pharmacol. 2010;627(1-3):269-75. PMID 19853596
[8] Rutten K, Van donkelaar EL, Ferrington L, et al. Neuropsychopharmacology. 2009;34(8):1914-25. PMID 19262466
[9] Reneerkens OAH, Rutten K, Steinbusch HWM, Blokland A, Prickaerts J. A promising target for cognition enhancement. Psychopharmacology. 2009;202(1-3):419-443. doi:10.1007/s00213-008-1273-x.
[10] Barad M, Bourtchouladze R, Winder DG, Golan H, Kandel E. Proc Natl Acad Sci USA. 1998;95(25):15020-5. PMID 9844008
[11] Lelkes Z. Pharmacol Biochem Behav. 1998 Aug;60(4):835-9.
[12] Block F1. Neuroreport. 2001 May 25;12(7):1507-11.
[13] Chen RW. Neurosci Lett. 2007 May 17;418(2):165-9. Epub 2007 Mar 18.
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