Main Points

  • Forskolin increases cAMP in the brain, a molecule involved in memory formation, concentration, and long-term memory.
  • Supplementation may attenuate fatigue symptoms.


  • Forskolin (derived from the plant Coleus forskohlii), used in traditional Indian Ayurvedic medicine

Forskolin and Cognitive Function

cAMP Activation 

Forskolin increases cellular levels of a molecule called cyclic adenosine monophosophate (cAMP).

Elevated levels of cAMP are associated with focused concentration and long-term memory. This molecule is also believed to mediate mechanisms in the brain where memories are formed.