Shopping Cart

Focus Stack™

For Cognitive Support, Mental Performance, and Increased Clarity
Rated 4.0 out of 5
1 Review
Regular price $117.50 List price

$122.85

  • For Cognitive Support
  • Increased Mental Performance
  • Brain Fog-Busting Clarity

Maintain Healthy Brain Cells, Think Faster and Solve Problems with Ease.

Help your brain grow new neurons which are the foundation to all mental tasks, and improve your processing speed!

Support your overall brain health with MycoMINDs' natural antioxidant increasing formula.

MycoMIND helps combat oxidative stress and promotes healthy function of your Mitochondria.

Acetylcholine Brain Food can help you concentrate and communicate effectively.

Great for any social situation whether you're at the office, in the classroom, or spending time with loved ones.

Better Brain, Better Life

Use CILTEP to remain sharply motivated and focused for hours.

CILTEP removes brain fog leaving you clear to communicate to anyone with ease.

On those long days where you normally hit a wall. Use CILTEP to power through and remain engaged all day long.

Benefits include increased motivation, improved concentration, mood, and enhanced ability to study.

CILTEP is the premier natural nootropic for obtaining laser-like focus for hours and creating long lasting memories.

CILTEP is designed to induce long-term potentiation in the brain which is crucial to the formation of new memories.

How This Stack Works

MycoMIND™ is a brain cell optimizer designed to promote Nerve Growth Factor and Mitochondrial Biogenesis.

Research suggests that the natural compounds in MycoMIND™ can grow new neurons and mitochondria, the foundation of all mental tasks. It’s the most essential daily nootropic.

  • Maintains healthy brain cells †
  • Promotes healthy mitochondrial function & biogenesis †
  • Supports graceful brain aging †
  • Helps combat oxidative stress †

This natural formula combines Organic Lion’s Mane mushroom extract with BioPQQ™ to support as many healthy brain cells as possible.

MycoMind™ contains natural ingredients that work synergistically to highlight the unique benefits of medicinal mushrooms. 

In this case that mushroom is Lion’s Mane. With only two ingredients, MycoMind™ supports cellular energy production in the brain, it confers neuroprotective properties related to the growth and health of new brain cells, and it supports overall brain health by increasing antioxidant status.

Lion’s Mane Mushroom

The original discovery of Lion’s Mane’s ability to increase Nerve Growth Factor (NGF) occurred in 1991 and is credited to Japanese scientists, Dr. Kawagishi. This discovery presented a massive paradigm shift in the way science looks at brain cells. No longer a finite number that decreases over our lifespan, entire fields of scientific research have since been devoted to maintaining - even increasing - brain cell counts for enhanced cognitive function and longevity.

Since that time, numerous studies have confirmed that this naturally occurring mushroom contains active compounds that stimulate NGF synthesis in human cells and promotes neurite outgrowth via activation of the JNK pathway (Jun amino-terminal kinase) This was proven in vivo. When they fed mice with Lions Mane powder there was an increase in the level of NGF mRNA expression in the hippocampus. [3,4]

A study published in the September 2014 edition of the International Journal of Molecular Science confirmed that Lion’s Mane contains a compound known as Erinacine A that effectively scavenges free radicals, inhibiting inflammation and helps repair injured brain and nerve cells. [5]

Based on a 2010 study published in Biomedical Research, Lion’s Mane seems to decrease anxiety and depression symptoms. [6]

According to a 2008 Japanese study, Lion’s Mane seems to halt and reverse (increased score on cognitive function scale) cognitive decline in 50-80 year old Japanese men and women who suffered from mild cognitive impairment. The effect weren’t permanent and the scores declined after 4 weeks of stopping the ingestion of Lion’s Mane. [7]

BioPQQ

Pyrroloquinoline quinone, or PQQ for short, is a coenzyme that was discovered in 1979. PQQ is involved in many of the body’s natural metabolic processes and PQQ supplementation has been shown in studies to provide neuroprotective activity, anti-oxidative activity, and mitochondrial biogenesis.

Our source, BioPQQ is the industry leader for pyrroloquinoline quinone. Simply put, PQQ helps us create new mitochondria. [8]

In recent years, a substantial body of evidence has underscored the importance of mitochondrial function in maintaining energy balance, minimizing oxidative stress and promoting longevity. Mitochondrial function has been examined in many aspects, including metabolic, neural and age-related conditions. PQQ deficiency decreases the size, number and function of mitochondria in rodents, and supplementation reverses these effects.[9,10,11]

Supplementation with PQQ has been shown to improve memory and reasoning, while more studies indicate that PQQ offers neuro-protective properties via reduction of oxidative damage. In a randomized, double-blind study of 71 middle aged individuals, PQQ supplementation over 12 weeks significantly improved short term memory and demonstrated the ability to prevent memory loss. [12,13,14]

In 2012, Japanese researchers performed the first human study examining the effect of BioPQQ on stress, fatigue, and sleep. They concluded that supplementing with PQQ improved sleep, leading to reduced negative mental states, relief of fatigue and rise of positive mood. Other important conclusions from this study were that “mood also was improved by diminishing feelings of fatigue, and improved measures of appetite, sleep, pain and obsession with no adverse effects.” [15]

A 2016 study examining the impact of BioPQQ using near-infrared spectrometry (NIRS) found that cerebral blood flow in the prefrontal cortex was increased by the administration of PQQ. “The results suggest that PQQ can prevent reduction of brain function in aged persons, especially in attention and working memory.” [16]

CILTEP

CILTEP® is a natural formula designed to safely enhance the brain's ability to form vivid, long-lasting memories and remain sharply motivated and focused for hours.

Users of CILTEP® often report:

  • Increased motivation and mental endurance
  • Improved concentration and alertness
  • Improved mood and social ease
  • Enhanced ability to study

Beat Brain Fog!

Brain Fog is the worst! We all have those moments where it's just impossible to focus, or when the one thing we were thinking of is just stuck at the tip of the tongue!

As we get older these things tend to get worse, but the good news is they don't have to. 

There's a reason why thousands of entrepreneurs, doctors, firefighters and students around the world are using CILTEP® to boost their focus, motivation and memory. 

Introducing CILTEP® (sil-tep) for Focus and Memory

CILTEP® is a natural supplement that can help you achieve a higher state of focus and concentration with enhanced memory formation.

The formula is designed to induce long-term potentiation (LTP) in the brain. 

LTP is a crucial mechanism involved in the formation of new memories and the strengthening of neural synapses.


The formula works by:

PDE4 Inhibition + Increasing cAMP = Long-Term Potentiation

Developed by Abelard Research, the CILTEP® Formula is a protected by United States Patent and Trademark Office US9149457B2.

Natural Stacks is currently involved in multiple placebo-controlled, double-blind University studies on its effectiveness.

PDE4 INHIBITION

PDE4 is an enzyme that breaks down cAMP molecules, messenger systems that relay signals in the brain. 

Inhibition of PDE4 blocks the breakdown of cAMP, and thereby increases levels of cAMP within brain cells.

This has been shown to lead to increased cognition, improved long term memory, increased wakefulness, and neuroprotection. [3,4,5,6,7,8]

There have been several natural PDE4 inhibitors identified in herbal preparations including luteolin, which is present in artichoke extract. It also inhibits PDE 1 through 5 which have both shown beneficial activity with regards to synaptic plasticity. [1,2]

Artichoke Extract is a safe, effective and natural PDE4 Inhibitor. [1,2] CILTEP contains 900 mg of the highest quality Artichoke Extract in each serving.

INCREASING cAMP

The herb Forskolin (active compound extracted from the root of the Coleus Forskohlii plant) has been shown to naturally increase cAMP levels. 

It activates the enzyme adenylyl cyclase which then increases intracellular levels of cAMP. [10]

CILTEP features premium Coleus Forskohlii standardized for 20% Forskolin. There are 4 mg of Forskolin in each serving of CILTEP.

Increasing cAMP and inhibiting its degradation supports Long-Term Potentiation (LTP).

Summary: PDE4 Inhibition + Increasing cAMP → LTP → Supports optimal mental performance

ACETYLCHOLINE
Acetylcholine Brain Food™ is designed to promote the production of acetylcholine, a neurotransmitter essential to mental processing. Research suggests that the natural compounds in Acetylcholine Brain Food™ are associated with memory and cognitive function.

  • Improved attention to detail†
  • Better mental clarity†
  • Faster thinking†
  • Cuts through brain fog†

To make acetylcholine, the brain needs two elements: an acetyl group and a choline molecule.

An acetyl group is a type of simple molecular building block of organic chemistry with a chemical formula of C2H30. The acetyl group is usually present in the brain as Acetyl-CoA. Choline and the acetyl group are grouped together by the enzyme Choline Acetyltransferase (ChAT). 

They are both stored in neurons, released, and then broken down by another enzyme called acetylcholinesterase (AchE). To increase levels of acetylcholine, we use the following approach:

  • Create more acetyl-CoA molecules to provide acetyl groups to ChAT for acetylcholine production.
  • Provide more choline in choline producing (cholinergic) neurons for use by ChAT.
  • Increase or upregulate the activity of ChAT.
  • Decrease the activity of AchE.

Acetylcholine Brain Food™ contains the essential raw materials for the brain to increase production, achieve balance, and maintain prolonged activity of the neurotransmitter acetylcholine -- the Learning Molecule.


MycoMIND™

MycoMIND™ is a brain cell optimizer designed to promote Nerve Growth Factor and Mitochondrial Biogenesis.

Research suggests that the natural compounds in MycoMIND™ can grow new neurons and mitochondria, the foundation of all mental tasks. It’s the most essential daily nootropic.

Maintains healthy brain cells†

Promotes healthy mitochondrial function & biogenesis†

Supports graceful brain aging†

Helps combat oxidative stress†

Learn More About MycoMIND™
Ciltep®

CILTEP® is a natural nootropic designed to safely enhance the brain's ability to form vivid, long-lasting memories and remain sharply motivated and focused for hours.

Increased focus and mental sharpness

Increased motivation and mental endurance

Enhanced sense of novelty, presence, and awareness

Improved recall and memory formation

Learn More About Ciltep®
Acetylcholine Brain Food™
Acetylcholine Brain Food™ is designed to promote the production of acetylcholine, a neurotransmitter essential to mental processing. Research suggests that the natural compounds in Acetylcholine Brain Food™ are associated with memory and cognitive function.

Improved attention to detail†

Better mental clarity†

Faster thinking†

Cuts through brain fog†

Learn More About Acetylcholine Brain Food™

Suggested Use

MYCOMIND
Take a serving of 2 capsules 1 to 2 times per day for brain health and mental sharpness, or as directed by a healthcare practitioner.

U.S.A. manufactured in a cGMP facility. Natural Stacks proudly uses only the highest quality ingredients.

CILTEP
Take 1-3 capsules in the morning immediately upon waking on an empty stomach, or as directed by a healthcare practitioner. Do not take more than 3 capsules per day.

Some users find that a moderate dose of caffeine in the morning and/or early afternoon extends and optimizes results (We recommend SMART CAFFEINE®).

CILTEP® can be taken daily, however we advise taking 1-2 days off per week (weekends for example).

U.S.A manufactured in a GMP facility. Natural Stacks proudly uses only the highest quality ingredients.

CILTEP® is protected by U.S. Patents US10058529B2 and US9149457B2.

ACETYLCHOLINE
Take a serving of 2-4 capsules to support mental processing speed, or as directed by a healthcare practitioner.

Do not exceed 8 capsules per day.

U.S.A. manufactured in a cGMP facility. Natural Stacks proudly uses only the highest quality ingredients.

Great value icon 1 Great value icon 2 Great value icon 3 Great value icon 4 Great value icon 5

Open Source

Most companies use "proprietary blends" so they don't have to tell you the amount of each ingredient in their formulas. At Natural Stacks we believe it's your right to know exactly what you're putting into your body. We proudly publish our innovative formulas and ingredient suppliers in an open source format.

Learn About Our Commitment To Transparency

100% Happiness Guarantee

If for whatever reason you're unsatisfied with your Natural Stacks supplements, you can keep the full bottle on us and we'll refund your money. Anything after the first bottle, we'll ask that you return for a refund.

User Reviews

average rating 4.0 out of 5
Based on 1 review
  • 5 Stars
    0 Reviews
  • 4 Stars
    1 Review
  • 3 Stars
    0 Reviews
  • 2 Stars
    0 Reviews
  • 1 Star
    0 Reviews
100% of reviewers would recommend this product to a friend
1 Review
Rated 4 out of 5
Review posted

Surprised with Lion's Mane

The best part of the stack for me was the Lion's Mane+PQQ. I already knew that PQQ was a winner, but had no idea how profoundly the LM would work. Ciltep is great as long as I need to focus. Otherwise, it can make me a little OCD. The A-Choline...I find it makes me a little anxious, and that it's better when I take it on separate days from the Ciltep. I also find that I'm better when taking these at half the suggested. Just my 2 cents...Doug

Loading...
Was this helpful?

Citations & References

MYCOMIND

1. Kawagishi, H. Lion’s Mane: The Anti-Dementia Effect of Lion's Mane Mushroom and it’s Clinical Application. Townsend Letter for Doctors and Patients. APRIL 2004

2. Mori K. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.Phytother Res. 2009 Mar;23(3):367-72. doi: 10.1002/ptr.2634.

3. Mori K. Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells. Biol Pharm Bull. 2008 Sep;31(9):1727-32.

4. Lai PL. Neurotrophic properties of the Lion's mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms. 2013;15(6):539-54.

5. Lee K-F, Chen J-H, Teng C-C, et al. Protective Effects of Hericium erinaceus Mycelium and Its Isolated Erinacine A against Ischemia-Injury-Induced Neuronal Cell Death via the Inhibition of iNOS/p38 MAPK and Nitrotyrosine. International Journal of Molecular Sciences. 2014;15(9):15073-15089. doi:10.3390/ijms150915073.

6. Nagano M. Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res. 2010 Aug;31(4):231-7.

7. Mori K. Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.Phytother Res. 2009 Mar;23(3):367-72. doi: 10.1002/ptr.2634.

8. Chowanadisai W. Pyrroloquinoline quinone stimulates mitochondrial biogenesis through cAMP response element-binding protein phosphorylation and increased PGC-1alpha expression. J Biol Chem. 2010 Jan 1;285(1):142-52. doi: 10.1074/jbc.M109.030130. Epub 2009 Oct 27.

9. Stites T, Storms D, Bauerly K, Mah J, et al. Pyrroloquinoline quinone modulates mitochondrial quantity and function in mice. J Nutr. 2006;136(2):390-6.

10. Bauerly KA, Storms DH, Harris CB, Hajizadeh S, et al. Pyrroloquinoline quinone nutritional status alters lysine metabolism and modulates mitochondrial DNA content in the mouse and rat. Biochim Biophys Acta. 2006;1760(11):1741-8.

11. Zhu BQ, Simonis U, Cecchini G, Zhou HZ, et al. Comparison of pyrroloquinoline quinone and/or metoprolol on myocardial infarct size and mitochondrial damage in a rat model of ischemia/reperfusion injury. J Cardiovasc Pharmacol Ther. 2006;11(2):119-28.

12. He B. The roles of PI3K/Akt pathway in proliferation of Schwann cells promoted by pyrroloquinoline quinone. Zhonghua Zheng Xing Wai Ke Za Zhi. 2010 Jan;26(1):53-6.

13. Ohwada K, Takeda H, Yamazaki M, Isogai H, et al. Pyrroloquinoline quinone (PQQ) prevents cognitive deficit caused by oxidative stress in rats. J Clin Biochem Nutr. 2008;42:29-34]

14. Nakano M, Ubukata K, Yamamoto T, Yamaguchi H. Effect of pyrroloquinoline quinone (PQQ) on mental status of middle-aged and elderly persons. FOOD Style 21 2009;13(7):50-53.

15. Nakano, M. Effects of Oral Supplementation with Pyrroloquinoline Quinone on Stress, Fatigue, and Sleep. Functional Foods in Health and Disease 2012, 2(8):307-324 Page 307 of 324

16. Itoh, Y. Effect of the Antioxidant Supplement Pyrroloquinoline Quinone Disodium Salt (BioPQQ™) on Cognitive Functions. Adv Exp Med Biol. 2016;876:319-25.

CILTEP
1. Brown JE, Rice-evans CA. Luteolin-rich artichoke extract. Free Radic Res. 1998;29(3):247-55. PMID 9802556 32

2. Yu MC, Chen JH, Lai CY, Han CY, Ko WC. Eur J Pharmacol. 2010;627(1-3):269-75. PMID 19853596

3. Rutten K, Van donkelaar EL, Ferrington L, et al. Neuropsychopharmacology. 2009;34(8):1914-25. PMID 19262466

4. Reneerkens OAH, Rutten K, Steinbusch HWM, Blokland A, Prickaerts J. A promising target for cognition enhancement. Psychopharmacology. 2009;202(1-3):419-443. doi:10.1007/s00213-008-1273-x.

5. Barad M, Bourtchouladze R, Winder DG, Golan H, Kandel E. Proc Natl Acad Sci USA. 1998;95(25):15020-5. PMID 9844008

6. Lelkes Z. Pharmacol Biochem Behav. 1998 Aug;60(4):835-9.

7. Block F1. Neuroreport. 2001 May 25;12(7):1507-11.

8. Chen RW. Neurosci Lett. 2007 May 17;418(2):165-9. Epub 2007 Mar 18.

9. Ammon HP, Müller AB. Forskolin: from an ayurvedic remedy to a modern agent. Planta Med. 1985;51(6):473-7. PMID 17345261

10. Seamon KB, Daly JW. Forskolin: a unique diterpene activator of cyclic AMP-generating systems. J Cyclic Nucleotide Res. 1981;7(4):201-24. PMID 627800

11. Linus Pauling Institute. Micronutrient Information Center: Vitamin B6. http://lpi.oregonstate.edu/mic...

12. Broadley KJ (March 2010). Pharmacol. Ther. 125 (3): 363–375. doi:10.1016/j.pharmthera.2009.11.005. PMID 19948186.

13. Lindemann L, Hoener MC (May 2005). "A renaissance in trace amines inspired by a novel GPCR family". Trends Pharmacol. Sci. 26 (5): 274–281. doi:10.1016/j.tips.2005.03.007. PMID 15860375.

14. Inano A1. Acetyl-L-carnitine permeability across the blood-brain barrier and involvement of carnitine transporter OCTN2. Biopharm Drug Dispos. 2003 Nov;24(8):357-65.

15. Scafidi S, Fiskum G, Lindauer SL, et al. Metabolism of acetyl-L-carnitine for energy and neurotransmitter synthesis in the immature rat brain. Journal of neurochemistry. 2010;114(3):820-831. doi:10.1111/j.1471-4159.2010.06807.x.

16. Pettegrew, JW. Molecular Pyschiatry. Nov. 2000, Volume 5, Number 6, Pages 616-632.

17. Cooke SF. Plasticity in the human central nervous system. Brain. 2006 Jul;129(Pt 7):1659-73. Epub 2006 May 3.

18. Bliss TV1. A synaptic model of memory: long-term potentiation in the hippocampus. Nature. 1993 Jan 7;361(6407):31-9.

19. Bryan J1. Psychological effects of dietary components of tea: caffeine and L-theanine. Nutr Rev. 2008 Feb;66(2):82-90. doi: 10.1111/j.1753-4887.2007.00011.x

20. Curtin BF. Forskolin, an inducer of cAMP, up-regulates acetylcholinesterase expression. Mol Cell Biochem. 2006 Oct;290(1-2):23-32. Epub 2006 Aug 19.

21. Guilarte TR. Neurochem Res. 1989 Jun;14(6):571-8.

22. White HL. Acetyl-L-carnitine as a precursor of acetylcholine. Neurochem Res. 1990 Jun;15(6):597-601.

ACETYLCHOLINE
De jesus moreno moreno M. Cognitive improvement in mild to moderate Alzheimer's dementia after treatment with the acetylcholine precursor choline alfoscerate: a multicenter, double-blind, randomized, placebo-controlled trial. Clin Ther. 2003;25(1):178-93. PMID 12637119

Szutowicz A, Bielarczyk H, Jankowska-kulawy A, Pawełczyk T, Ronowska A. Acetyl-CoA the key factor for survival or death of cholinergic neurons in course of neurodegenerative diseases. Neurochem Res. 2013;38(8):1523-42. PMID 23677775

Houten SM, Wanders RJ. A general introduction to the biochemistry of mitochondrial fatty acid β-oxidation. J Inherit Metab Dis. 2010;33(5):469-77. 20195903

Arsenio L, Bodria P, Magnati G, Strata A, Trovato R. Effectiveness of long-term treatment with pantethine in patients with dyslipidemia. Clin Ther. 1986;8(5):537-45. PMID 3094958

Malaguarnera M, Gargante MP, Cristaldi E, et al. Acetyl L-carnitine (ALC) treatment in elderly patients with fatigue. Arch Gerontol Geriatr. 2008;46(2):181-90. PMID 17658628


*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

To guarantee fast shipping and the best possible service, we're transferring you to our Australian website.

Let's Go