Study Finds Coriander Seeds Reduce Anxiety

Anxiety disorders are some of the most common mood disorders affecting people of all ages and all walks of life in some form or another.

Anxiety is usually manifested in the form of excessive worry or fear, and a feeling of apprehension towards future events.

Typical symptoms include heart palpitations, chest pain, sweating, irritability, rapid breathing, and muscle tightening.

The usual treatment options include lifestyle change, medication, and behavioral therapy.

Do They Help?

While therapy is normally successful, the drugs often cause sideeffects for many people, and may not be effective for the whole neurological mechanism of anxiety.

Therefore, natural alternatives that may be more effective are highly sought after.

Many plants contain bioactive compounds that are very effective in treating various conditions, and are far better tolerated.

Coriander is one such plant, widely known for its medicinal properties.

A recently published study on coriander examines how its seeds could safely alleviate anxiety.

Read on for more info.

What’s Important

Anxiety disorders are highly treatable when the right approach is taken.

However, the neurological mechanism behind anxiety involves several different neurotransmitter pathways that are imbalanced as a result of anxiety.

The problem with synthetic drugs is that they work to balance only a small fraction of the full spectrum.

Coriander (Coriandrum sativum L.) is a popular and versatile herb, indigenous to the Mediterranean, and cultivated around the world.

Its leaves and seeds are used in both medicine and the culinary world.

It’s known to have antibacterial and anti-inflammatory properties and to also help lower blood pressure and blood sugar, as well as promote digestion and gut health.

Previous research has also indicated that it has sedative and hypnotic effects. [1]

Some Details

The study was animal-based and it involved supplementing the mice with either coriander seed extract or Diazepam for 16 days.

During this time they were exposed to restraint stress to induce a state of anxiety, followed by behavioral evaluation.

What the scientists found was useful:

  • Coriander seed extract demonstrated significant anti-anxiety effect, possibly acting through the same pathway as Diazepam;
  • When there is anxiety, the expression of the neurotransmitter responsible for regulating anxiety is decreased. In this study, coriander seed extract rebalanced this neurotransmitter;
  • Coriander seed extract increased the levels of dopamine and noradrenaline in all brain regions, compared to Diazepam which increased their levels only in the hippocampus;
  • The extract also increased serotonin levels, but only in the hippocampus, like Diazepam;
  • It showed a possible reversal to neuronal damage due to chronic stress.
  • The Takeaway

    The results from this study show a great promise and seem attainable.

    Finding new, safe, and effective ways to treat anxiety is a welcome prospect, so it remains to see how it plays out.

    Resource: Sahoo, S.; Brijesh, S. Anxiolytic activity of Coriandrum sativum seeds aqueous extract on chronic restraint stressed mice and effect on brain neurotransmitters. Journal of Functional Foods 2020, 68, 103884. doi: 



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