This Form Of Magnesium Reverse Brain Aging and Restores Neurons

The only magnesium to cross the blood brain barrier, MagTein can reverse the aging process, lower brain age by 9 years, restore lost executive function, and increase synapse density in as little as 2-4 weeks.

Increased cognitive function resulting from 6 weeks of MagTein supplementation.


Today's guest on Episode #32 of the Optimal Performance Podcast is Dr. Jennifer Gu, Vice President of Research & Development for AIDP. (AIDP is the company who holds the patent for MagTein - the backbone of our MagTech formulation)

MagTein, a patented form of magnesium-l-threonate, is the only magnesium supplement that crosses the blood barrier. In doing so, it elevates brain concentrations of magnesium, restores neurons, enhances synapse density and decreases brain age.


"MagTein brings brain cells back to life for a more effective brain and better quality of life at every stage"
What You'll Learn About MagTein from Dr. Jennifer Gu in this episode:
  • Why AIDP is "The Authority" on nutritional ingredients and premium scientific supplements
  • The discovery of MagTein in the 1990's in the Department of Neuroscience at UCLA
  • How MagTein occurs naturally and what allows it to cross our blood-brain barrier when no other magnesium can...
  • What "Milk of Magnesia" and other anti-constipation medications reveal about most magnesium supplements
  • Hospital's IV doses of magnesium sulfate increase BLOOD magnesium by 300%, but only increase BRAIN levels by 15%. When this same form of magnesium is taken as a supplement, even LESS reaches the brain - that's why you're not noticing anything from lower quality magnesium supplements.
  • MagTein, even at 1/3 of the RDA for magnesium, results in 10X Concentration in BRAIN magnesium vs the rest of the body.
  • Increasing synapse density so you get improved memory and better overall brain function - as reported by MIT scientists and Nobel Prize winning co-author Susumu Tonegawa in Neuron - the Gold Standard in Journals for neuroscientists.
  • REVERSING AGING! MagTein lowers brain age by 9 years and had been demonstrated to restore dying neurons.
  • Achieving optimal brain levels in 2-4 weeks, and staying there by maintaining MagTein levels. (see image below)
  • Discovering why cognitive function declines with aging and how MagTein is REVERSING this
  • Researchers are working to make "more effective forms" of for an upcoming study from Stanford!
  • How Dr. Gu chooses her supplements and which company's to trust
  • Get more from Dr. Jennifer Gu
  • Dr. Gu's Top 3 tips to #LiveOptimal


Links & Resources

MagTein Website


MagTein Press Release

Increase Synapse Density Study

Lowers Brain Age Full Study  

Stock up on MagTech HERE so you can increase synapse density, lower brain age, revive dying neurons, and make your brain more effective at every stage of life!

OPP #32 Transcript


Ryan Munsey: Alright. Happy Thursday, all you optimal performers. Welcome to another episode of the Optimal Performance Podcast. I'm your host, Ryan Munsey. Today, I wanna welcome in a very special guest, Doctor Jennifer Gu. Doctor Gu, thanks for hanging out with us.

Jennifer Gu: Hello. Hi, Ryan. Hello, everyone. Good morning.

Ryan Munsey: Good morning. Yeah. So, for everybody listening, Doctor Gu is the Vice President of Research and Development for a company called AIDP.

This is the company that sources and manufactures the Magtein that we use in our MagTech products. So, we recently published some studies. We didn't publish them, we shared these studies that have been published recently showing some of their work and some of the benefits of magnesium L-threonate and specifically Magtein.

So, we're gonna talk a lot about the mechanisms of action there and let Doctor Gu tell us what's going on, what the benefits are, and some of the potential uses in the future for this. Before we really dive in, a couple of housekeeping notes. As always, go to to see the video version of this as well as get the show notes, any links and resources to the stuff that we talk about today.

Doctor Gu has already mentioned that she has some really cool slides and visuals that will accompany some of the information she shares. So, we will either build that into the video or we'll have that for you guys on the blog post. Of course, make sure you head over to iTunes. Leave us a five-star review. Let us know how much you're enjoying that show. With that, let's dive in. Doctor Gu, tell us what AIDP is all about. What do you guys do?

Jennifer Gu: Oh, thanks, Ryan, for having me. AIDP is a leading supplier of nutritional ingredients. The company was established in 1996, so we're celebrating 20 years in the industry.

Ryan Munsey: Okay.

Jennifer Gu: 20 years a lot about the quality of the company, so we have to say we're the experts on the ingredients of all the nutritional products and how they do, which one is good, and what the science behind them. Especially in the last 10 years, we have developed dozens of research-based proprietary ingredient. Magtein is one of the most interesting and also, most successful ingredient we have developed over the last 10 years.

Ryan Munsey: That's one of the things that we really appreciate about you guys is ... for our listeners and people who follow us, they know that we operate with 100% transparency. We're opensource, we like natural ingredients, we like things that are rooted and founded in science, proven by science. We like to share it and discuss the science of everything that we do. So, this is gonna be really cool for us and for our listeners. You mentioned Magtein being one of the things that has been very successful for you guys. Can you talk to us about maybe why you guys started looking for what eventually became Magtein? How did it come to be?

Jennifer Gu: Yes, Magtein actually is the very interesting ingredient. It was developed 20 years ago, started 20 years ago from a group of scientists. Actually, the primary investigator started in early 1990s, late 1980s, early 1990s, when he was doing his PhD at UCLA Department of Neuroscience. So, during those time, the goal for the research group is to develop ingredients that can lead to new drugs for treating neurodegenerative disease, like Alzheimer's, all these that have made impact in our life, so that was the main goal.

So, the research started as a typical drug screening research. It started at a cell culture to look at all the ingredients that actually can activate the neuron cells to lead to the signal connectivity. Magtein was accidentally discovered. In fact, Magtein is a natural ingredient. It's naturally present in our body and so, that actually was first discovered, a cell culture, and then, was tested in animals, and then, recently, in humans. So, it was a very unique ingredient that discovers through this pathways and was demonstrated in cell culture, in animal studies, in humans to be really effective and to demonstrate the safety, the mechanisms.

It's become a very important and successful ingredient for our industry.

Ryan Munsey: Now, you mentioned that it's something that occurs naturally. What are some natural sources of it or how does it get in our body other than in supplement form?

Jennifer Gu: Okay. So, actually, Magtein, it's a magnesium product, okay? It's magnesium because of unique liquid. This liquid is a vitamin C metabolite, major vitamin C metabolite. So, we take a lot of ingredients with vitamin C in our body, so we naturally have this liquid in our body. We have the magnesium in our body, so these two ingredients is already present in our body, so that's how-

Ryan Munsey: Okay.

Jennifer Gu: Yeah, how it is. Yeah, they're present.

Ryan Munsey: No, and we've talked to our listeners and our followers on the blog already about how Magtein, specifically magnesium L-threonate is the only form of magnesium that can cross the blood-brain barrier. What's special about Magtein that allows it to do that?

Jennifer Gu: Okay. So, what's the research have find out, the liquid threonate can promote the magnesium across the blood-brain barrier to the body. So, this is actually very interesting. You probably noticed that a lot of the anti-constipation product over-the-counter has magnesium in it. So, most of the time, you take magnesium compounds and they do not get absorbed and that is the mechanism it uses to have the anti-constipation effect, okay? The Magtein is different. Magtein has been shown to be very effective to be absorbed into the intestines. So, you do not have these diarrhea problems and then, most uniquely, is that it can cross blood-brain barrier, okay?

So, in animal studies, we have compared in the first publication in Neuron.

We have compared the Magtein with the most bioavailable organic magnesium and inorganic magnesium, okay? Only Magtein are able to cross the blood-brain barrier to raise the brain magnesium levels effectively and then, to have all these benefits, okay? Give you example. When people have involved in accident, in a brain trauma, they bring to the hospitals. In those cases, the emergency room will give you a IV injection of magnesium sulfate. In these cases, your blood magnesium level will increase about 300%, but your brain magnesium level only increase about 15%, and that is under IV, okay? Talking about just taking a supplement, you would have minimum magnesium to the brain, and that's why people have not noticed anything while taking all the magnesium and compounds until Magtein.

So, when you take Magtein, even though we only deliver about one-third of the RDA daily allowed magnesium ... and, you can feel it for most people. You can feel it to the brain and also, the unpublished data indicated that threonate has a 10 times concentration in our human's brain compared to other site of the body, which indicates that mechanistically threonate can bring Magtein, magnesium, to the brain effectively.

Ryan Munsey: That's awesome, and some of the other results from your study show that it's able to increase synapse density?

Jennifer Gu: Yes. In the first publication on this product, it was discovered in ... it was published in 2010 in Neuron. We know Neuron is the most prestigious neurological journals, okay? So, when that was published, it was published from MIT with a Nobel Prize winner as the coauthor. So, when it was published, it showed, demonstrated the Magtein was the only magnesium effectively raise the brain magnesium levels. Also, it demonstrated, at the cellular level, how Magtein can increase the neuron connectivity, the plasticity. Then, later on, at the behavioral level, how that correlated with the memory change in terms of short-term memory, longterm memory in young animals, older animals, middle-aged animals, and in, also, the spatial memory and cognitive functions, so that was well-demonstrated.

Ryan Munsey: Yeah, and that was really cool. That was something that we ... we shared that and we actually wrote a blog post talking about that. I think one of the coolest things for us was that it shows the ability to demonstrate lowering brain age by nine years. Yeah, go ahead.

Jennifer Gu: Okay, yes. Yes. That's very, very exciting, so the uniqueness about Magtein is that it is well-supported by science. It was found through the traditional drug searching pathway. So, when the ... it's not like you just take a compound and you find out what it do. So, what happened is that it first started as a screening pathway and then, find out, identify, this compound as the most bring available by available compound and then, studied in animal models for the mechanisms of action at the cellular level, signaling level, histology level, behavioral level. Then, at the end, recently, it was researched in human clinicals.

So, in a most recently published human clinicals, what having demonstrated that Magtein is not just improving the memory. It improving the overall brain functions and we're using the drill-making test and we're using the published data to look about what's so-called, called the, "brain age", okay? When the participants, before they take the Magtein, their real biological age is about 57 average, but their brain age, at the time, was about 69, and that is expected because these individuals, they are normal individuals. But, they are complaining they have some memory deficient.

They have some anxiety issues, so a lot of them are have some problems in memories. So, their brain age is older than their real age, okay? But, after three months of taking this product, it shifted their brain age by this test to 60, so that's about nine years of reversal based on the scientific measurements, and that is very close to the actual age, which is 57, so that is really astonishing.

Ryan Munsey: Yeah.

Jennifer Gu: We were impressed, we knew the function already.

Ryan Munsey: Yeah.

Jennifer Gu: I'm taking it myself, so I know how good it works, but to see it in a scientific way is really nice to be documented.

Ryan Munsey: Oh, that's huge. You're able to reverse aging. So, my question regarding that is, what do you guys know or what do we know about those effects in people who don't have or not complaining about memory loss or their brain age is not older than their biological age?

Jennifer Gu: Well, I think most of people, we have variations of how people performs. Some people are very good at the brain power and other people are less, but we are not comparing one person versus the other. We're comparing the person versus when he was at the peak age, which when he was young. Everything was normal. So, majority of the people, when they actually are at the older age, about my age, 50 and the later, they would have a significant decrease in their brain power, not necessarily they are in a problem stage, not necessarily they are diagnosed with Alzheimer's, with anything, just like majority of the participants.

They're not diagnosed with any problems.

Those people, when they are actually at those older age, they have decrease of brain power.

So, when Magtein will be able to restore their brain power to their optimum level, so that is the role of Magtein does, okay? So, for the very few people, in fact, in human clinicals, we have about 80% of response rate, which means that 20% of them do not respond.

So, nothing will be 100% responding, that's what it is, but 80% is a great number already for the people to be able to respond, and that is demonstrated about the repeat order rate we have seen for people who are taking Magtein because they feel the differences. For example, for myself, I consider myself a normal person, but I have tremendous response to Magtein when I take it, okay?

It increased my working efficiency, it increased my working power, not necessarily memory because it's hard for normal people to read the memory unless maybe 10 years later, I will be able to read my memory more clearly. But, now, to me, it's not necessary memory. It's the ability to focus, ability to work efficiently, and ability to have a relaxed mood. All these are the things I feel and for people who do not have a significant memory deficiency.

Ryan Munsey: Okay. Now, are there compounding effects? Meaning, the longer we take it, the more enhancement we get?

Jennifer Gu: Not necessarily a compounding effect. I would like to put it this way. So, when you look at the human clinicals, the effect of Magtein improves about ... different people are different. So, let's say about one month, two weeks to one month ... then, for most people, it peaks. Some people can go longer, some people are shorter, but, average, about a month, it peaks, okay? Then, it plateaus and so, the idea is that you bring back to your optimum level. Then, you stay there.

What's interesting is that in the animal study, we have done a very interesting experiment, is that we feed animals, it goes about two weeks to peak and then, stays there. When we discontinue the use of Magtein, the behavior goes back. It takes about two weeks to goes back to its background levels. Then, if you giving them Magtein again, it goes back again, which tells us that our body have a way of maintaining these levels, okay? So, we need to supplement it to maintain at the optimum level, to be effective. If we stop using it, it's going to disappear because we're supplementing very little amount.

We're only giving people one-third of the daily allowed magnesium levels.

Ryan Munsey: Right.

Jennifer Gu: Yeah, so it needs to be supplemented to have the benefits constantly.

Ryan Munsey: Yeah, and I'm glad you mentioned ... that's the second time now, that it's one-third of the RDA because we've had people ask that question when they look at our label, "Why is there less in here than what I'm used to seeing?" We explain that, but I think you do a much better job of communicating that than we do.

Jennifer Gu: As a scientist, we always strive to deliver the smallest amount. Actually, Doctor Liu, the primary investigator from MIT, we talked about it. So, one of the goal is to deliver as little as possible because we're giving a nutrition to people daily use. We want to be as safe as possible, so we want to give as little as possible as not as effective, so that's why it's a small amount.

Ryan Munsey: Okay. Now, let's go back to when we're talking about being able to restore executive function. If you're able to fix this or reverse it, restore it, does that mean that you guys have been able to glean some insight on why people are experiencing the decline in cognitive or executive function?

Jennifer Gu: Yes. We actually have a very nice slide showing how the neurodegenerative disease occurs, okay? So, what happens, I will give you a brief description of that mechanism. So, what happens is that our neuron cells, when we're young, they're very vibrant. In molecular level, they have a lot of receptors on the cell's surface. So, when we receive signals, it's a great response, okay? Then, over the time, what happens is that some of these vibrant brain cells will become grey cells, okay? Grey cells means that they're quiescent. They have done regulated their receptors, so they're sitting there. They're not responding, okay?

Then, over the time, these grey cells will be, if you continue, grow, aging, and continue to be activated, they will actually go to apoptosis.

They become to die, okay? So, all of these neurodegenerative drugs, they're [inaudible 00:20:23] neurotransmitters, right? So, they can only activate the cells when they're vibrant. They have receptors, they can only respond when there is healthy cells there. But, when they become grey cells, they become dead cells. They cannot respond, so that's why all the drugs, if you look at the label, it says they only works at early stage. They only work half a year when they stop working. Why? Because there's not enough cells there at the end. In fact, it can push the cells, go to apoptosis faster. Magtein works very differently, Magtein works about letting the cell rest, okay?

So, when you rest well, you bring back these receptors back, so the cells can become vibrant again, become useful, become to receive more signals, okay? So, it works very differently with the traditional mechanisms, and that is why there's so much interest because of the unique mechanisms, because it's a useful ... a brain rejuvenating ingredient.

Ryan Munsey: That's fascinating. It's so cool. I know, in the press release that you guys put out recently, there were hints about further clinical trials and advancing through. What can you tell us about the future, what's in store? This sounds so exciting for treatment of Alzheimer's or other neurodegenerative diseases.

Jennifer Gu: Ryan, when I first looked at the publications in 2010, I was so excited. In fact, Neuron, as you know ... I worked at Caltech, I was doing my post at Caltech many years ago. So, when we were there, if you have a publication in Neuron, you were a guaranteed professor there. So, Neuron was the most prestigious neurological journals.

Ryan Munsey: Right.

Jennifer Gu: So, that paper, when it was published in 2010, it was the three most downloaded articles in Neurons, that just showed how much interest it generated in the research community. There was also over a dozen of media publications on this ingredient, so it was very top science discovery in many scientists' view. So, what happening is that, in animal studies, that's when you can discover the mechanisms, discover how it really works. It was beautifully done, okay? In humans, we did a normal nutritional ... human clinical on normal people, okay? But, as a nutritional ingredients that Magtein is, we are not supposed to claim for disease treatment for anything because it's not intended for.

Ryan Munsey: Right, right.

Jennifer Gu: But, however, there were efforts that are made to using Magtein in clinical trials on Alzheimer's disease and other neurological diseases, and that has some huge potential and some very interesting discoveries. But, because of the regulation ... we once applied for the regulation. So, the Magtein, at current formulation, at current dosage, was really for the memory and cognition purpose.

Ryan Munsey: Okay, so I have two questions based on some of that. Number one, if you're able to go further down the road with the clinical stuff, will that affect Magtein's status as a nutritional supplement? Is there danger of us losing that as an over-the-counter thing?

Jennifer Gu: We would intend to separate it in terms of a different format of Magtein versus a drug product because drug product are [inaudible 00:24:32], are normally used in different forms and more effective forms, so that is the idea. Also, as you know, that the drug development world normally takes a long time to be finalized.

Ryan Munsey: Right.

Jennifer Gu: So, one of the things Magtein can do versus drugs is that it can really benefit people who are at early stage of memory problems, who are normal individual like me, who actually are through the aging process and naturally have some brain defect, lose of some of the brain power. So, Magtein are also very effective for normal people and not just the people who are at the very severe conditions of disease status. So, I think that's the benefit, Magtein as a nutrition for normal people. We are striving to separate the normal population who can benefit from the nutritional effects of Magtein versus a people who are at the very late stage of a neurodegenerative disease. They might need a different form of Magtein.

Ryan Munsey: Well, that's another question I had in my head as you were giving that answer. You were talking about the drug form being more effective. How do you make this more effective?

Jennifer Gu: That is something ... I think it's more proprietary and there is a independent company that are making a effort on that part of the formulation and discovery.

Ryan Munsey: Okay.

Jennifer Gu: They are also testing in the diseased conditions and that is a totally different pathway. It's a pharmaceutical approach and are currently working.

Ryan Munsey: Okay, that's not the one that the press release talked about going on at Stanford?

Jennifer Gu: Yeah, it is.

Ryan Munsey: Okay, okay.

Jennifer Gu: It is.

Ryan Munsey: So, we'll keep our eye out for that.

Jennifer Gu: Okay.

Ryan Munsey: Okay.

Jennifer Gu: Well, actually, tremendous interest from medical communities, not only on the potential role of different forms of Magtein in terms of the Alzheimer's disease, but, also, the anxiety issues like people on the depression, people on the anxiety. Because, if you look at the animal studies, because the mechanism of it, there's common mechanisms for these different disease conditions-

Ryan Munsey: Yeah.

Jennifer Gu: Well, they were using that for different areas of the treatments.

Ryan Munsey: Will you elaborate on that for our listeners? Talk about the similarity or the commonalities that those disease states share.

Jennifer Gu: Yes, I definitely can.

Ryan Munsey: Okay.

Jennifer Gu: But, just bear in mind that Magtein is not intended for any of the treatment. I just want to go over that through the mechanistic point-of-view.

Ryan Munsey: Right, right.

Jennifer Gu: So, we talked about Magtein works at the neurodegenerative conditions, right? So, neurodegenerative is the cells become quiescent and become to die. So, when you have enough cells death, death of the ... empty of the neuron cells, there's no signals going on, that's why you have the problems, right? So, Magtein was able to reverse those quiescent cells back to the useful levels. So, we talked about that mechanisms ... and, improve the neuron density, plasticity. Okay, so that is in the mechanisms of the neurodegenerative issues. Then, we talked about the anxiety, okay? Anxiety, actually, there's a publication in animals about how Magtein can works in the anxiety models.

But, to put it in a more understandable way, what happens is that our anxiety is coordinated by different parts of the brain. So, one part is that you acquire ... called "amygdala", that is the reason you acquire the initial stress, okay? For example, when a soldier sent to the Iraqi war, so they saw a dramatic event, the brain recognize that dramatic event, and that is important because that's how people survive. You have to recognize danger, okay? But, when we acquire that initial stress, then other part of the body, prefrontal cortex and other regions of the memory, they begun to process this dangerous information, okay?

They're telling our brain ... it says, "Okay, so this is dangerous. But, now, we're in a different environment. We're safe, so we can control this." But, the problem for some people who have this anxiety issue is that their control is not working very well. So, they stop, so they're still in that dangerous condition, so they're stressed and worried, so that is where the prefrontal cortex controls. Magtein works on the prefrontal cortex to help to control these traumatic events, so that is why Magtein works on the memory region, works on the prefrontal cortex region, but not works on the initial amygdala region, which acquired the anxiety.

So, put in another way, we can acquire the anxiety event well, but, then, Magtein helps to control the memory, control the stress management, so that is how Magtein works to help with these conditions.

Ryan Munsey: Okay, very cool. Very cool. Are there other neurological disorders or neurodegenerative disorders that you guys are exploring possible solutions with?

Jennifer Gu: There's interest in Parkinson's disease, okay?

Ryan Munsey: Okay, okay.

Jennifer Gu: So, there's interest in Parkinson's disease. There's interest in ADHD in the children, so because the areas controlling these actions are located in similar areas and we have demonstrated Magtein are able to improve those areas, that has been shown to play a role in these diseases, so that's why there's a lot of community contacting us to try to collaborate in these areas of research.

Ryan Munsey: That's so cool.

Jennifer Gu: Yeah, it is. It is.

Ryan Munsey: So, can you tell us how magnesium or Magtein has impact on ADHD or Parkinson's?

Jennifer Gu: I think these ones ... ADHD was more like the anxiety management, those mechanisms, okay?

Ryan Munsey: Okay.

Jennifer Gu: In terms of Parkinson's disease, I think it's the same brain regions. It's the same brain regions that can probably ... Magtein can impact, that can control the movement. The movement, those muscle movements are controlled by some areas of the brain. So, Magtein can impact those areas and to help with the movement of those muscle control areas.

Ryan Munsey: Okay. So, in all of these things that MagTech or Magtein is able to help with, does it really just come down to the fact that it's able to cross the blood-brain barrier and actually get where it needs to be?

Jennifer Gu: Yes, that's a important point. Majority of the effects was the magnesium's effect and magnesium is a very important mineral in our body. It's the coenzyme for 300 different metabolic reactions in our body, so our brain really needs it to be functional. Majority of the compound cannot really goes to the brain and Magtein can really do it very effectively. So, I agree with you that Magtein is very unique in this perspective. Yeah.

Ryan Munsey: Okay. What's next for you, what has you excited right now?

Jennifer Gu: What is really exciting is about the ability of Magtein to work as a preventive effect as a nutrition. It can benefit different populations of people, people who are healthy that wants to be rejuvenating of the brain power and people are at a problem stage will need some help to make their brain more effective, right? It actually has been demonstrated to be very effective for the pioneer users, people like your customers who actually went out and tried it and find to be effective, but very few ... majority of people do not know it yet.

Ryan Munsey: Right.

Jennifer Gu: So, we fully expected that through your programs, through awareness of the marketing and people's feedbacks on this product, more and more users will be able to benefit with this product. So, we want it to be a more general nutrition that can help people to have a better quality of life at different stage of their brain ages.

Ryan Munsey: Yeah, that's very cool. We certainly love it and we want everybody to be taking it, so we'll do everything we can to get the word out for you guys.

Jennifer Gu: Yeah, wonderful. Thank you, thank you for your support.

Ryan Munsey: Yeah.

Jennifer Gu: That's wonderful.

Ryan Munsey: Yeah.

Jennifer Gu: Yeah.

Ryan Munsey: So, Doctor Gu, before we let you go, two questions. One, where can our listeners get more of you, your research, what you guys are doing?

Jennifer Gu: We have a website called, which actually has a lot of information on this. Most importantly, Magtein is a very well science-supported ingredient. Majority of the research are published in very prestigious peer-reviewed journals. So, those articles can be found in those website, at least, the references. People can read it by themselves if they're interested and so, there's a lot of ... and, with a lot of feedback from consumers themselves will only add to the more information of this ingredient.

Ryan Munsey: Okay, great. Now, the question that we ask all of our podcast guests, what are your top three tips for our listeners to live optimal?

Jennifer Gu: Eat well, that is very important. When we're young, we did not notice the importance of it. When we come to a certain age, eating well make a huge difference over five, 10 years, very different if we eat well. Eat well, eat healthy. That's number one.

Ryan Munsey: Okay.

Jennifer Gu: Exercise. Of course, exercise also make a difference and we all know that.

Ryan Munsey: Yeah.

Jennifer Gu: Of course, the third is to choose the right nutritional supplements. A lot of people talk to me and said, "Doctor Gu, I eat a lot of the supplements and I do not notice the difference." So, I have to say that supplements, sometimes, when you have enough nutrition, then you do not notice the differences. However, if you do not have enough of it, that is when you're ... to the certain age, you do not have all the nutrients. You need it, you are losing a lot of nutrients, your absorption level is lower. Your secretion level is higher, then you begin to lose those balance and that is time when you take your status, and that become a very important part of the health regimen.

Ryan Munsey: So, that's really interesting. How can Our listeners distinguish for themselves where that point is? For somebody like you who's very educated on this and very in tune with their body, that may be easy for you to say, "Oh, well, I'm low", or, "I'm deficient in this, I need to supplement with it."

Jennifer Gu: Yes, you're absolutely right. One of the issue challenging the nutritional industry is knowledge because there's so many different ingredients out there. It's hard for normal consumers to know which ones to take. So, normally, the way I do for myself is that, sometimes, I do not know which nutrition I'm losing, I am lacking, okay? One of the things that ... when you do the check, you wanted to check your nutrient levels, okay? So, those, some of the test will tell you, for example, your PH level, your different mineral level, those kind of things, that actually is beneficial. So, I think, in some point of the life, when you're at a certain age, after 50s or something, we should do a test of that to know our nutritional status, okay? Then, a second thing is that if you really do not know ... for example, I do take multivitamins at this age because I do not know which one I'm lacking. So, it's more like a guarantee, okay?

Ryan Munsey: Okay.

Jennifer Gu: Then, the third part is that if I notice some areas that I need to be supplemented, I do tend to take a supplement from a qualified company because those companies, a company like your company, actually have a lot of research. They have done their research and they looked at all the ingredients in this area. So, they have picked up for me the ingredients that have these ... for example, the brain functions, you have picked up ingredients that have solid science, safety [inaudible 00:39:21] demonstrated in these areas and put into a product. So, when I take it, if I notice the benefits, most likely, that's the ingredients I'm lacking.

Ryan Munsey: What is your filtering process? You mentioned certain supplement companies. How do you decide whether or not this is a company that you wanna trust or try?

Jennifer Gu: You do have to look at the levels of science. For me, levels of science support and they know what they're talking about if they have experts behind the ingredients, if they have solid publications behind ingredients. Those are important criteria for selecting the product that I use and should be the important criteria for consumers to select their ingredients and their products to use.

Ryan Munsey: Okay. Well, we've got an expert behind one of our ingredients and that's you. So, thank you for being the expert behind Magtein.

Jennifer Gu: I don't consider myself expert on Magtein.

Ryan Munsey: Yeah, yeah. So, Doctor Gu, this has been awesome. Thank you so much for sharing your time and your wisdom with us. Listeners, thank you, guys, for tuning in. Make sure you head over to to see the video version of this. We'll have links, we'll have resources, some of the publications that we mentioned. We'll have some slides, so you could see a visual on some of the things that we talked about. If you enjoyed the Optimal Performance Podcast, please think about somebody you know who will benefit from this. Share it with them, so that we can, as Doctor Gu said earlier, reach more people, help more people, and help more people live a better life. So, until next Thursday, thanks for listening. We'll talk to you guys later.

Speaker 2: Shout out to the guys over at Natural Stacks.

Speaker 4: Start optimizing your mental and physical performance, optimize yourself.




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